[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Names and Identifiers

Name	4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-beta-L-threo-pentofuranose
Synonyms	4-(HydroxyMethyl)-1,2-O-isopropylidene-3-O-benzyl 4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-beta-L-thr... 4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-β-L-threo-pentofuranose 4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-a-D-erythro-pentofuranose 4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-beta-L-threo-pentofuranose β-L-threo-Pentofuranose, 4-C-(hydroxymethyl)-1,2-O-(1-methylethylidene)-3-O-(phenylmethyl)- ((3aR,6R,6aR)-6-(Benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5,5-diyl)dimethanol [(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol [(3aR,6R,6aR)-6-(Benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5,5-diyl]dimethanol (non-preferred name) [(3aR,6R,6aR)-5-(hydroxymethyl)-2,2-dimethyl-6-phenylmethoxy-6,6a-dihydro-3aH-furo[2,3-d][1,3]dioxol-5-yl]methanol
CAS	72261-44-0
InChI	InChI=1/C16H22O6/c1-15(2)20-12-13(19-8-11-6-4-3-5-7-11)16(9-17,10-18)22-14(12)21-15/h3-7,12-14,17-18H,8-10H2,1-2H3/t12-,13-,14+/m1/s1

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Physico-chemical Properties

Molecular Formula	C16H22O6
Molar Mass	310.35
Density	1.29
Melting Point	70-71 ºC
Boling Point	442.5±45.0 °C(Predicted)
Flash Point	221.4°C
Vapor Presure	1.3E-08mmHg at 25°C
pKa	13.95±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.575

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Introduction

4-(Hydroxymethyl)-1, is an organic compound with the following chemical structure:

Nature:
The compound is a solid with a white to pale yellow color. It is insoluble in water at room temperature, but soluble in common organic solvents such as ethanol, dimethylformamide, etc. It has a melting point of about 118-122°C.

Use:
The compound is often used as an important intermediate in organic synthesis. It can be used in the synthesis of various important bioactive molecules, such as drugs, pentofuranose base in natural product synthesis, etc. In addition, it can also be used in the fields of drug modification, ligand design and nucleic acid chemistry.

Preparation Method:
The preparation method of the compound is roughly divided into two steps. First, 2,3-O-isopropylidene-D-threose was reacted with formaldehyde by acid catalysis to give 4-(hydroxymethyl)-1,2-O-isopropylidene-3-O-carboxaldehyde-D-threose. Then, it is reacted with benzyl alcohol under alkaline conditions to obtain the final product 4-(Hydroxymethyl)-1, -2.

Safety Information:
At present, there are few toxicological and safety studies on this compound. Therefore, when using this substance, it is necessary to follow relevant laboratory practices and personal protective measures. In addition, the compound should be handled and stored to avoid ignition and contact with skin, eyes and mucous membranes. For detailed information on the use and disposal of the substance, it is recommended to refer to the relevant safety information and chemical literature.

Last Update：2024-04-09 21:01:54

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol

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[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol

4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-beta-L-threo-pentofuranose

CAS: 72261-44-0

Molecular Formula: C16H22O6

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Names and Identifiers

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Physico-chemical Properties

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Introduction

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[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol Request for Quotation

4-(Hydroxymethyl)-1,2-O-isopropylidene-3-O-benzyl-beta-L-threo-pentofuranose

CAS: 72261-44-0

Molecular Formula: C16H22O6

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Names and Identifiers

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Physico-chemical Properties

[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol - Introduction

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[(3aR,6R,6aR)-6-benzyloxy-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[4,5-d][1,3]dioxol-5-yl]methanol